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Sarcoidosis is a disease involving abnormal collections of inflammatory cells that form lumps known as granulomas. The disease usually begins in the lungs, skin, or lymph nodes. Less commonly affected are the eyes, liver, heart, and brain.

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Furthermore, knockdown of Fgf21 in the liver of Cnot6l−/− mice restores sensitivity to nutrient excess and reverses the decrease seen in diet-induced weight gain (Fig. 6). It is evident that there is a significant rescue of liver-specific…

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